Applications

FA

Synonyms:

GPR30 Agonist, AC1MJFYZ, MLS001242405

Formulation:

Crystalline solid

Chemical Name:

1-[4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-8-yl]ethanone

Molecular Formula:

C₂₁H₁₈BrNO₃

Molecular Weight:

412.3

CAS Number

881639-98-1

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

References:

Bologa, C. G., Revankar, C. M., Young, S. M., Edwards, B. S., Arterburn, J. B., Kiselyov, A. S., ... & Prossnitz, E. R. (2006). Virtual and biomolecular screening converge on a selective agonist for GPR30.Nature chemical biology,2(4), 207-212.

Blasko, E., Haskell, C. A., Leung, S., Gualtieri, G., Halks-Miller, M., Mahmoudi, M., ... & Horuk, R. (2009). Beneficial role of the GPR30 agonist G-1 in an animal model of multiple sclerosis.Journal of neuroimmunology,214(1), 67-77.

Kumar, R., Balhuizen, A., Amisten, S., Lundquist, I., & Salehi, A. (2011). Insulinotropic and antidiabetic effects of 17β-estradiol and the GPR30 agonist G-1 on human pancreatic islets.Endocrinology,152(7), 2568-2579.