Animal-Free Recombinant Human GDF-3
货号：AF-120-22-5,AF-120-22-20,AF-120-22-50,AF-120-22-100,AF-120-22-250,AF-120-22-500,AF-120-22-1000
规格：5ug,20ug,50ug,100ug,250ug,500ug,1mg
价格：795,1787,6430,10488,17691,26286,40516
产品类型：细胞因子添加物
品牌：PeproTech
| 产品详情产品编号：AF-120-22产品描述：GDF-3 is a member of the TGF-β superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF-β family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia that characterizes Type 2 diabetes. Recombinant Human GDF-3 is a 26.0 kDa non-disulfide-linked homodimer containing two 114 amino acid polypeptide chains.Manufactured using all Animal-Free reagents.Source:E.coliSynonyms:Growth/Differentiation Factor-3, Vgr-2, UNQ2222/PRO248AA Sequence (monomer):AAIPVPKLSC KNLCHRHQLF INFRDLGWHK WIIAPKGFMA NYCHGECPFS LTISLNSSNY AFMQALMHAV DPEIPQAVCI PTKLSPISML YQDNNDNVIL RHYEDMVVDE CGCGPurity:≥ 98% by SDS-PAGE gel and HPLC analyses.Biological Activity:Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. TheED50for this effect is 100-150 ng/ml.Calculated Molecular Weight:26 kDaAccession Number:Q9NR23Gene ID:9573Country Of Origin:USANot for human use. |
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