Recombinant Human IL-1RA
货号:200-01Ra-100,200-01Ra-1000,200-01Ra-20,200-01Ra-250,200-01Ra-500
规格:100ug,1mg,20ug,250ug,500ug
价格:1418,9379,582,4092,6082
产品类型:细胞因子添加物
品牌:PeproTech
| 产品描述:Interleukin-1 receptor antagonist (IL-1RA) is a naturally-occurring, inflammatory-inhibitor protein. It inhibits the activity of IL-1α and IL-1β by competitively blocking their binding to type I and type II receptors. IL-1RA is produced by corneal epithelial cells, monocytes, neutrophils, macrophages, and fibroblasts. Therapeutically, IL-1RA may help in the treatment of sepsis, cachexia, rheumatoid arthritis, chronic myelogenous leukemia, asthma, psoriasis, and inflammatory bowel disease. Recombinant Human IL-1RA is a 17.2 kDa protein consisting of 153 amino acid residues.来源:E.coli氨基酸序列:MRPSGRKSSK MQAFRIWDVN QKTFYLRNNQ LVAGYLQGPN VNLEEKIDVV PIEPHALFLG IHGGKMCLSC VKSGDETRLQ LEAVNITDLS ENRKQDKRFA FIRSDSGPTT SFESAACPGW FLCTAMEADQ PVSLTNMPDE GVMVTKFYFQ EDE别名:IL-1Ra, ICIL-1RA, IRAP, IL-1RN纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:Determined by its ability to inhibit the IL-1α stimulation of murine D10S cell. The expectedED50is 20-40 ng/ml in the presence of 50 pg/ml of IL-1α.Calculated Molecular Weight:17.2 kDaAccession Number:P14778Gene ID:3554交叉反应:Frog,Human,Human + Virus,Mouse,Mouse + Virus,Rat原产国:USA |