Animal-Free Recombinant Human IL-1β
货号:AF-200-01B-2,AF-200-01B-10,AF-200-01B-100,AF-200-01B-50,AF-200-01B-250,AF-200-01B-500,AF-200-01B-1000
规格:2ug,10ug,100ug,50ug,250ug,500ug,1mg
价格:1250,2830,16550,9930,28960,43030,66220
产品类型:细胞因子添加物
品牌:PeproTech
产品详情产品编号:AF-200-01B产品描述:IL-1β is a proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes, and other epithelial cells. Both IL-1α and IL-1β bind to the same receptor and have similar, if not identical, biological properties. These cytokines have a broad range of activities including the stimulation of thymocyte proliferation by inducing IL-2 release, B cell maturation and proliferation, mitogenic FGF-like activity, and the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant Human IL-1β is a 17.3 kDa protein containing 153 amino acid residues.Manufactured using all Animal-Free reagents.Source:E.coliSynonyms:Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)AA Sequence:APVRSLNCTL RDSQQKSLVM SGPYELKALH LQGQDMEQQV VFSMSFVQGE ESNDKIPVAL GLKEKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTKGG QDITDFTMQF VSSPurity:≥ 98% by SDS-PAGE gel and HPLC analyses.Biological Activity:Determined by its ability to stimulate the proliferation of mouse D10S cells. The expectedED50is ≤ 0.001 ng/ml, corresponding to a specific activity of ≥ 1 x 109units/mg.Calculated Molecular Weight:17.3 kDaAccession Number:P01584Gene ID:3553crossreactivity:Frog,Human,Monkey,Mouse,Rabbit,Rat,SheepCountry Of Origin:USANot for human use. |