Murine IL-13
货号：210-13-10,210-13-100,210-13-1000,210-13-2,210-13-250,210-13-50,210-13-500
规格：10ug,100ug,1mg,2ug,250ug,50ug,500ug
价格：1418,11069,44326,582,19355,6634,28757
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching, resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 are cross-species reactive. Recombinant Murine IL-13 is a 12.3 kDa protein consisting of 111 amino acid residues.来源:E.coli别名:NC300 (Human), P600 (Murine)氨基酸序列:MPVPRSVSLP LTLKELIEEL SNITQDQTPL CNGSMVWSVD LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS YTKQLFRHGP F纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:TheED50as determined by the dose-dependent proliferation of TF-1 cells was≤ 4.0 ng/ml, corresponding to a specific activity of≥ 2.5 x 105units/mg.Calculated Molecular Weight:12.3 kDaAccession Number:P20109Gene ID:16163交叉反应:Human,Mouse,Rat原产地:USA仅用于科研，不能用于临床和诊断。 |
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