Animal-Free Recombinant Human β-NGF
货号:AF-450-01-20,AF-450-01-100,AF-450-01-250,AF-450-01-500,AF-450-01-1000
规格:20µg,100ug,250ug,500ug,1mg
价格:1250,2830,8080,12010,18480
产品类型:细胞因子添加物
品牌:PeproTech
| 产品描述:β-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. β-NGF is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. β-NGF also acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival. The functional form of Recombinant Human β-NGF is a non-covalently-linked homodimer of two 13.5 kDa, polypeptide monomers that each contain 120 amino acids and three disulfide bonds, which are required for biological activity.Manufactured using all Animal-Free reagents.来源:E.coli别名:NGF-β, beta-Nerve Growth Factor氨基酸序列:SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVRRA纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The expectedED50is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106units/mg.Calculated Molecular Weight:27 kDaAccession Number:P01138Gene ID:4803交叉反应:Chicken,Hamster,Human,Mouse,Rat原产国:USA |