Animal-Free Recombinant Human M-CSF
货号:AF-300-25-10,AF-300-25-100,AF-300-25-1000,AF-300-25-2,AF-300-25-250,AF-300-25-50,AF-300-25-500
规格:10ug,100ug,1mg,2ug,250ug,50ug,500ug
价格:2830,18090,72380,1250,31660,10850,47040
产品类型:细胞因子添加物
品牌:PeproTech
| 产品描述:M-CSF is a potent hematopoietic factor produced by a variety of cells, including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. It is a key regulator of cellular proliferation, differentiation, and survival for blood monocytes, tissue macrophages, and their respective progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness and fertility. M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis. It facilitates hematopoietic recovery after bone marrow transplantation. Human M-CSF is reactive in murine systems, but the murine molecule exhibits no activity on human cells. Recombinant Human M-CSF is a 36.8 kDa homodimeric protein consisting of two 159 amino acid polypeptide subunits.Manufactured using all Animal-Free reagents.来源:E.coli别名:Macrophage Colony Stimulating Factor, CSF-1, MGI-IM氨基酸序列:MEEVSEYCSH MIGSGHLQSL QRLIDSQMET SCQITFEFVD QEQLKDPVCY LKKAFLLVQD IMEDTMRFRD NTPNAIAIVQ LQELSLRLKS CFTKDYEEHD KACVRTFYET PLQLLEKVKN VFNETKNLLD KDWNIFSKNC NNSFAECSSQ GHERQSEGS纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:TheED50was determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106units/mg.Calculated Molecular Weight:36.8 kDaAccession Number:P09603Gene ID:1435交叉反应:Human,Monkey,Mouse,Rat |