Recombinant Human IL-31
货号:200-31-10,200-31-100,200-31-1000,200-31-2,200-31-250,200-31-50,200-31-500
规格:10ug,100ug,1mg,2ug,250ug,50ug,500ug
价格:1418,11069,44326,582,19355,6634,28757
产品类型:细胞因子添加物
品牌:PeproTech
| 产品描述:Human IL-31 is a T cell-derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (also known as gp130-like receptor or IL-31RA) and Oncostatin-M receptor (OSMR). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, JAK1, and JAK2 signaling pathways. IL-31-regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Recombinant Human IL-31 is a 15.8 kDa protein containing 141 amino acid residues.别名:Interleukin-31氨基酸序列:SHTLPVRLLR PSDDVQKIVE ELQSLSKMLL KDVEEEKGVL VSQNYTLPCL SPDAQPPNNI HSPAIRAYLK TIRQLDNKSV IDEIIEHLDK LIFQDAPETN ISVPTDTHEC KRFILTISQQ FSECMDLALK SLTSGAQQAT T来源:E.coli纯度:Greater than 98% by SDS-PAGE gel and HPLC analyses.生物活性:Measured by its ability to induce STAT3 activation in human U87 cells.Calculated Molecular Weight:15.8 kDaAccession Number:Q6EBC2Gene ID:386653交叉反应:Human原产地:USA仅用于科研,不能用于临床和诊断。 |