Recombinant Human Leptin
货号:300-27-1000,300-27-200,300-27-5mg
规格:1mg,200ug,5mg
价格:2570,1050,7700
产品类型:细胞因子添加物
品牌:PeproTech
| 产品描述:Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in variousin vivomodels. Recombinant Human Leptin is a 16.0 kDa protein containing 147 amino acid residues.来源:E.coli别名:Obesity protein (OB)氨基酸序列:MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSSKQKVTGL DFIPGLHPIL TLSKMDQTLA VYQQILTSMP SRNVIQISND LENLRDLLHV LAFSKSCHLP WASGLETLDS LGGVLEASGY STEVVALSRL QGSLQDMLWQ LDLSPGC纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:PeproTech's Human Leptin is biologically active in theob/obmouse obesity model. Theob/obmice were treated via intraperitoneal injection once daily at a dose of 5 µg Leptin/gm of body weight for 7 days. Significant effects on body weight, food consumption, and plasma glucose levels were observed compared to saline-treated controls.Calculated Molecular Weight:16 kDaAccession Number:P41159Gene ID:3952交叉反应:Bacteria,Chicken,Human,Monkey,Mouse,Pig,Rat原产国:USA |