Anti-Mouse IL-4 SAFIRE Purified

2024-10-15

Anti-Mouse IL-4 SAFIRE Purified

货号:81112-25-100,81112-25-500

规格:100 μg,500 μg

价格:1744,2334

产品类型:抗体和染料

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalogue Number :81112-25

Description

The 11B11 monoclonal antibody specifically reacts with mouse 14 kDa cytokine IL-4, expressed by the activated NKT cells and mast cells. IL-4 is species-specific and stimulates the proliferation and differentiation of B lymphocytes. It upregulates the expression of IgE receptors and class II MHC antigen.

The 11B11 antibody neutralizes the IL-4 cytokine.

Additional Information

Clone

11B11

Format:

SAFIRE Purified

Applications

FC, FA, IHC, IF, ELISA

Reactivity

Mouse

Isotype:

Rat IgG1, kappa

Research Interest:Innate Immunity
Cell Type:T Cells

Preperation:

The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Formulation:

Phosphate-buffered aqueous solution, ph7.2.

References:

Abrams, John S.Immunoenzymetric assay of mouse and human cytokines using NIP-labeled anti-cytokine antibodies. John Wiley & Sons, Inc., 1995.

Ohara, J., and W. E. Paul. "Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1."Nature315.6017 (1985): 333.

Haak-Frendscho, M., Brown, J. F., Iizawa, Y. U. J. I., Wagner, R. D., & Czuprynski, C. J. (1992). Administration of anti-IL-4 monoclonal antibody 11B11 increases the resistance of mice to Listeria monocytogenes infection.The Journal of Immunology,148(12), 3978-3985.

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