Anti-Human IFN gamma SAFIRE Purified

2024-10-15

Anti-Human IFN gamma SAFIRE Purified

货号:80821-25-50,80821-25-500

规格:50ug,500 μg

价格:1210,3410

产品类型:抗体和染料

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalogue Number :80821-25

Description

The NIB42 monoclonal antibody specifically reacts with human interferon gamma, a multifunctional cytokine that is produced mainly by activated T and NK cells. Interferon gamma has anti-viral and anti-parasitic properties and plays an important role in the activation, growth, and differentiation of macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-α, to inhibit proliferation of normal and transformed cells. The NIB42 antibody neutralizes IFN-γ.

Additional Information

Clone

NIB42

Format:

SAFIRE Purified

Applications

FC, Neutralization,

Reactivity

Human

Isotype:

Mouse IgG1, kappa

Research Interest:Innate Immunity,Adaptive Immunity, Cytokines & Growth Factors
Cell Type:Th1 cells,NK and NKT Cells,T Cells

Preperation:

The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Formulation:

Phosphate-buffered aqueous solution, ph7.2.

References:

Meager, A. (1987). Antibodies against interferons: Characterization of interferons and immunoassays.Lymphockies and Interferons. A Practical Approach. Clemens, MJ, AG Morris, and AJH Gearing, eds. IRL Press Ltd. Oxford, 105.

Meager, A., Parti, S., Barwick, S., Spragg, J., & O'hagan, K. (1984). Detection of hybridomas secreting monoclonal antibodies to human gamma interferon using a rapid screening technique and specificity of certain monoclonal antibodies to gamma interferon.Journal of interferon research,4(4), 619-625.

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