Clone

5D3

Format:

PE

Applications

FC

Reactivity

Human

Isotype:

Mouse IgG2b, kappa

Preperation:

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Özvegy-Laczka, C., Laczkó, R., Hegedűs, C., Litman, T., Várady, G., Goda, K., ... & Sarkadi, B. (2008). Interaction with the 5D3 monoclonal antibody is regulated by intramolecular rearrangements but not by covalent dimer formation of the human ABCG2 multidrug transporter.Journal of Biological Chemistry,283(38), 26059-26070.

Zhou, S., Schuetz, J. D., Bunting, K. D., Colapietro, A. M., Sampath, J., Morris, J. J., ... & Sorrentino, B. P. (2001). The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype.Nature medicine,7(9), 1028-1034.

Bunting, K. D. (2002). ABC transporters as phenotypic markers and functional regulators of stem cells.Stem cells,20(1), 11-20.