Anti-Mouse CD38 SAFIRE Purified

2024-10-16

Anti-Mouse CD38 SAFIRE Purified

货号:10412-25-100,10412-25-500

规格:100 ug,500 ug

价格:1791,3693

产品类型:抗体和染料

品牌:Biogems

物种:人

宿主:小鼠

抗体亚型:IgG

荧光染料:Purified

Catalog Number :10412-25

Description

The 90 monoclonal antibody specifically bind to mouse CD38, a type II transmembrane glycoprotein. CD38 is expressed on activated T cells, plasma cells, monocytes, and macrophages. In the mouse as opposed to the human, CD38 expression is downregulated on mouse germinal center B cells and plasma cells. CD38 displays cyclase and hydrolase enzymatic activity and is involved in lymphocyte adhesion, activation, and cell signaling. Its ligand is CD31.

Additional Information

Clone

90

Format:

SAFIRE Purified

Applications

FC, FA

Reactivity

Mouse

Isotype:

Mouse IgG2a, kappa

Cell Type:B Cells,NK and NKT Cells,Monocytes and Macrophages,T Cells

Preperation:

The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Formulation:

Phosphate-buffered aqueous solution, ph7.2.

References:

Oliver, A. M., Martin, F., & Kearney, J. F. (1997). Mouse CD38 is down-regulated on germinal center B cells and mature plasma cells.The Journal of Immunology,158(3), 1108-1115.

Bean, A. G., Godfrey, D. I., Ferlin, W. G., Santos-Argumedo, L., Parkhouse, R. M. E., Howard, M. C., & Zlotnik, A. (1995). CD38 expression on mouse T cells: CD38 defines functionally distinct subsets of αβ TCR+ CD4− CD8− thymocytes.International immunology,7(2), 213-221.

Lund, F., Solvason, N., Grimaldi, J. C., Michael, R., Parkhouse, E., & Howard, M. (1995). Murine CD38: an immunoregulatory ectoenzyme.Immunology today,16(10), 469-473.

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