货号：343614

规格：100 tests

价格：4550

产品类型：流式抗体

品牌：Biolegend

物种：人

宿主：仓鼠

抗体亚型：IgG

荧光染料：APC

Description

CD34,also known as gp105-120, is a type I monomeric sialomucin-like glyco-phosphoprotein with an approximate molecular weight of 105-120 kD. It is selectively expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nervous tissue. CD34 is a commonly used marker for identifying human hematopoietic stem/progenitor cells. Based on different sensitivities, four groups of epitopes of CD34 have been described. CD34 mediates cell adhesion and lymphocytes homing through binding to L-selectin and E-selectin ligands.

• Isotype Control

• APC/Cy7 Mouse IgG2a, κ Isotype Ctrl

• Reactivity

• Human,Cross-Reactivity:Cynomolgus, Rhesus

• Formulation

• Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

• Preparation

• The antibody was purified by affinity chromatography and conjugated with APC/Cy7 under optimal conditions. The solution is free of unconjugated APC/Cy7 and unconjugated antibody.

• Concentration

• Lot-specific (please contacttechnical supportfor concentration and total µg amount, or use ourLookuptool if you have a lot number.)

• Storage & Handling

• The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.

• Application

• FC - Quality tested

• Recommended Usage

• Each lot of this antibody is quality control tested byimmunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells or 5 µl per 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

• Excitation Laser

• Red Laser (633 nm)

• Application Notes

• The 561 antibody recognizes a class III groupepitope, which is resistant to sialidase/glycolyprotease and chymopapain treatment.

• Application References

• 1. Croockewit AJ,et al.1998.Scand. J. Immunol.47:82.2. Rosenzweig M,et al.2001.J. Med. Primatol.30:36.