ANTI-HUMAN CD19 (HIB19) BIOTIN
货号:13-0199-80,13-0199-82
规格:25 UG,100 UG
价格:0,741
产品类型:流式抗体
品牌:eBioscience
抗原:CD19
物种:人
宿主:小鼠
抗体亚型:IgG
克隆号:HIB19
荧光染料:Biotin
| 抗体类型: | 单抗 | 同型对照: | IgG1, kappa |
| 免疫原性: | | 用法: | 1µg/test(Flow) |
| Description: The HIB19 monoclonal antibody reacts with human CD19, a 95 kDa transmembrane glycoprotein. CD19 is expressed by B cells during all stages of development excluding the terminally differentiated plasma cells. Follicular dendritic cells also express CD19. Together CD21, CD81, Leu13, MHC class II, and CD19 form a multimolecular complex that associates with BCR. Signaling through CD19 induces tyrosine phosphorylation, calcium flux and proliferation of B cells. The SJ25C1 antibody and the HIB19 monoclonal antibody recognize overlapping epitopes.Applications Reported: The HIB19 antibody has been reported for use in flow cytometric analysis.Applications Tested: This HIB19 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 1 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Filtration: 0.2 µm post-manufacturing filtered. |
| 数据 |
CD19 Antibody (13-0199-80) in FlowStaining of normal human peripheral blood cells with Anti-Human CD19 FITC (left), and PE (right). Autofluorescence is indicated by open histogram. Cells in the lymphocyte population were used for analysis. |
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| 参考文献: |
| 1.Journal of virologyAcquisition of host-derived CD40L by HIV-1 in vivo and its functional consequences in the B-cell compartment."13-0199 was used in Magnetic cell separation to investigate the biological functions of HIV virus-associated CD40L."Authors Imbeault M,Ouellet M,Giguère K,Bertin J,Bélanger D,Martin G,Tremblay MJ2.BloodCD1d-unrestricted human NKT cells release chemokines upon Fas engagement."13-0199 was used in Magnetic cell separation to investigate whether the Fas ligand was directly or indirectly chemotactic toward neutrophils, showing that CD1d-unrestricted human NKT cells release chemokines upon Fas engagement."Authors Giroux M,Denis F |