OCT4 Polyclonal Antibody

货号：PA5-85098

规格：100 µL

价格：4806

产品类型：流式抗体

品牌：Thermo Fisher

抗原：OCT4

物种：人/小鼠

宿主：大鼠

抗体亚型：IgG

荧光染料：其它

类型:	多抗	同型对照：	IgG
免疫原性：	human embryonal carcinoma cell line 2102Ep	用法：	2.0 µg/mL(ICC);10 µg/mL(IF);1 µg/mL(WB)

Product Specific InformationKeep as concentrated solution.Positive Control: 293T, A431, Jurkat, Raji, HeLa nucleus, Human ESC, mouse ESC.Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Target InformationOct4 is a maternally expressed octamer-binding protein that was the first transcription factor described for the early stages of development. Oct4 is one of the four Yamaka factors, necessary for embryonic stem cell pluripotency. Pluripotent stem (iPS) cells, can be created by expressing Oct4 and the transcription factors Sox2, Klf4 and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing Oct4, Sox2, KlfF4 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation.⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

数据

OCT4 Antibody (PA5-85098) in FlowFlow cytometry analysis of OCT4 in human embryonic stem cells using OCT4 polyclonal antibody (Product # PA5-85098) at a dilution of 1:100. Sample was then incubated with rabbit IgG (black) secondary antibody.

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