SSEA4 Monoclonal Antibody (MC813-70), Alexa Fluor 647
货号:SSEA421
规格:500 µL
价格:4994
产品类型:流式抗体
品牌:Thermo Fisher
抗原:SSEA4
物种:人
宿主:小鼠
抗体亚型:其它
克隆号:MC813-70
荧光染料:Alexa Fluor 647
Target InformationSSEA-4 (Stage-specific embryonic antigen 4) is a cell surface antigen, expressed along with SSEA-3, TRA-1-60 and TRA-1-81 in embryonic stem cells, embryonal carcinoma cells and induced pluripotent stem cells (iPS). In human cells, these surface markers are down-regulated during the differentiation process, while SSEA-1 is absent in undifferentiated human stem cells and upregulated on the cell surface after retinoic acid mediated differentiation. Conversely, in mouse stem cells, SSEA-1 expression decreases with differentiation while SSEA-3 and SSEA-4 expression increase.For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
数据 |
| SSEA4 Antibody (SSEA421) in FlowNtera2 cells were stained with Alexa Fluor® 647-conjugated anti-SSEA4 monoclonal antibody (Product # SSEA421). The negative profile represents unstained cells. |
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参考文献: |
| 1.Journal of tissue engineering and regenerative medicine Embryonic stem cells of the non-human primate Callithrix jacchus can be differentiated into definitive endoderm by Activin-A but not IDE-1/2. "SSEA421 was used in flow cytometry to compare the effects of IDE-1 and IDE-2 on the differentiation of common marmoset ESCs into the definitive endoderm germ layer." AuthorsDiekmann U,Naujok O,Blasczyk R,Müller T |