LIN28A Polyclonal Antibody

2024-10-17

LIN28A Polyclonal Antibody

货号:PA5-23408

规格:100 ug

价格:0

产品类型:流式抗体

品牌:Thermo Fisher

物种:人/小鼠/大鼠

宿主:兔

抗体亚型:IgG

荧光染料:Purified

类型:

多抗

同型对照:

IgG

免疫原性:

Synthetic peptide (117 CIGSERRPKGKSMQKRRSK 135) of LIN28 protein.

用法:

5 µg/mL(IHC (P));2.0 µg/mL(ICC);10 µg/mL(IF);1 µg/mL3-6 µg/mL(WB)

Target InformationLin-28 homolog A is a protein that in humans is encoded by the LIN28 gene. It is a marker of undifferentiated human embryonic stem cells and has been used to enhance the efficiency of the formation of induced pluripotent stem (iPS) cells from human fibroblasts. It encodes a cytoplasmic mRNA-binding protein that binds to and enhances the translation of the Igf2 mRNA. LIN28 has also been shown to bind to the let-7 pre-miRNA and block production of the mature let-7 microRNA in mouse embryonic stem cells.For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

数据

LIN28A Antibody (PA5-23408) in WBWestern blot analysis of LIN28 in human D3 cell lysate in the 1) absence and 2) presence of immunizing peptide and 3) mouse NIH 3T3 cell lysate using a LIN28 polyclonal antibody (Product # PA5-23408) at 5 µg/mL, 5 µg/mL and 3 µg/mL respectively. Goat anti-rabbit Ig HRP secondary antibody.

LIN28A Antibody (PA5-23408) in IHC (P)Immunohistochemical analysis of LIN28 in formalin-fixed, paraffin-embedded mouse testis tissue using an isotype control (top) and a LIN28 polyclonal antibody (Product # PA5-23408) (bottom) at 5 µg/mL.

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