ABCA4 Polyclonal Antibody

货号：PA5-78689

规格：100 µg

价格：2746

产品类型：免疫组化一抗

品牌：eBioscience

物种：人/小鼠/大鼠

宿主：兔

抗体亚型：IgG

荧光染料：Purified

类型:	多抗	同型对照：
浓度：		用法：	0.1-0.5 µg/mL(WB)
免疫原性：	A synthetic peptide corresponding to a sequence at the C-terminus of mouse ABCA4.

产品详细信息The synthetic peptide sequence is 1892-1903aa, TLLIQHHFFLTRAdd 0.2 mL of distilled water, will yield a concentration of 500 µg/mL.靶标信息ABCA4 (ATP-Binding Cassette, Subfamily A, Member 4), also known as ABCR, is a protein which in humans is encoded by the ABCA4 gene. ABCA4 is a member of the ATP-binding cassette transporter gene sub-family A (ABC1) found exclusively in multicellular eukaryotes. Using a whole genome radiation hybrid panel, Allikmets et al. (1997) mapped the ABCR gene to 1p21-p13. Allikmets et al. (1997) localized ABCR transcripts exclusively within photoreceptor cells, indicating that ABCR mediates the transport of an essential molecule (or ion) either into or out of photoreceptor cells. Molday et al. (2000) showed by immunofluorescence microscopy and Western blot analysis that ABCR is present in foveal and peripheral cone, as well as rod, photoreceptors. The results suggested that the loss in central vision experienced by patients with Stargardt macular dystrophy arises directly from ABCR-mediated foveal cone degeneration.⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

数据

ABCA4 Antibody (PA5-78689) in WBWestern blot analysis of ABCA4 in mouse brain tissue lysate using 50 µg per well. Sample was incubated with ABCA4 (Product # PA5-78689) at a dilution of 0.5 µg/mL.

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