Nkx2.5 Polyclonal Antibody
货号：PA5-47322
规格：100 µg
价格：5335
产品类型：免疫组化一抗
品牌：eBioscience
物种：人
宿主：山羊
抗体亚型：IgG
荧光染料：Purified
类型: | 多抗 | 同型对照： | |
浓度： | 0.2 mg/mL | 用法： | 5-15 µg/mL（IHC）；0.1 g/mL(WB) |
免疫原性： | E. coli-derived recombinant human NKX2.5 Gln24-Arg137 | | |
产品详细信息Reconstitute at 0.2 mg/mL in sterile PBS.靶标信息NKX2-5 is a transcription factor protein which plays a crucial role in cardiac development and differentiation. It is a low molecular weight protein of 35-38 kDa depending on phosphorylation status. Expression is mainly restricted to the heart. But during embryogenesis NKX2-5 expression has also been detected in spleen-precursor cells. Over expression of NKX2-5 resulted in expression of neuronal markers in C2C12 murine myogenic cells. Functionally it is involved in differentiation processes in heart development and in homeostasis and survival of cardiac myocytes as well maintains the initial muscle differentiation paradigm.
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