Nkx2.5 Monoclonal Antibody (4B11)

货号：MA5-18671

规格：100 µg

价格：4880

产品类型：免疫组化一抗

品牌：eBioscience

物种：人

宿主：小鼠

抗体亚型：IgG2b, kappa

荧光染料：Purified

类型:	单抗	同型对照：
浓度：	1 mg/mL	用法：	Assay-Dependent（ELISA）；Assay-Dependent（IP）；1-5 µg/mL(WB)
免疫原性：	NKX2-5 (NP_004378, 1 a.a. ~ 130 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa

产品详细信息Peptide Sequence: MFPSPALTPT PFSVKDILNL EQQQRSLAAA GELSARLEAT LAPSSCMLAA FKPEAYAGPE AAAPGLPELR AELGRAPSPA KCASAFPAAP AFYPRAYSDP DPAKDPRAEK KELCALQKAV ELEKTEADNA *靶标信息Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development (Shiojima et al., 1995 [PubMed 7665173]). It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart. Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation. Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation. CSX, the human homolog of murine Csx, has a homeodomain sequence identical to that of Csx and is expressed only in the heart, again suggesting that CSX plays an important role in human heart formation.

数据

Nkx2.5 Antibody (MA5-18671) in IP Immunoprecipitation of NKX2-5 transfected lysate using anti-NKX2-5 monoclonal antibody (Product # MA5-18671) and Protein A Magnetic Beads, and immunoblotted with NKX2-5 rabbit polyclonal antibody. Immunoprecipitation of NKX2-5 transfected lysate using anti-NKX2-5 monoclonal antibody (Product # MA5-18671) and Protein A Magnetic Beads, and immunoblotted with NKX2-5 rabbit polyclonal antibody.

二抗荧光二抗免疫组化一抗标签抗体

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