CD9 Polyclonal Antibody/CD9多克隆抗体
货号：PA5-85955
规格：100 µL
价格：4806
产品类型：免疫组化一抗
品牌：Thermo Fisher
抗原：Synthetic peptide corresponding to N-terminal of H
物种：人/小鼠/大鼠
宿主：兔
抗体亚型：IgG
荧光染料：其它
| 类型: | 多抗 | 同型对照： | |
| 浓度： | 1 mg/mL | 用法： | 1:100-1:200(Flow);1:200(ICC);1:200(IF);1:200(IHC);1:1,000(WB) |
靶标信息CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. CD9 belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression plays a critical role in the suppression of cancer cell motility and metastasis. CD9 is also considered as metastasis suppressor in solid tumors.
| 数据 |
| CD9 Antibody (PA5-85955) in FlowFlow Cytometric analysis of CD9 in Jurkat cells using a CD9 Polyclonal Antibody (Product # PA5-85955) at a dilution of 1:100, as seen in blue compared with an unlabelled control (cells without incubation with primary antibody; red). Goat anti rabbit IgG (FITC) was used as the secondary antibody.CD9 Antibody (PA5-85955) in IHC (P)Immunohistochemical analysis of CD9 of paraffin-embedded Mouse large intestine tissue using a CD9 Polyclonal antibody (Product #PA5-85955). Counter stained with hematoxylin. |
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