CD9 Polyclonal Antibody/CD9 多抗
货号：PA5-95868
规格：100 µL
价格：4732
产品类型：免疫组化一抗
品牌：Thermo Fisher
抗原：Recombinant fusion protein containing a sequence c
物种：人/小鼠
宿主：兔
抗体亚型：IgG
荧光染料：其它
类型: | 多抗 | 同型对照： | IgG |
浓度： | 8.66 mg/mL | 用法： | 1:500 - 1:2000(WB) |
产品详细信息Immunogen sequence: SHKDEVIKEV QEFYKDTYNK LKTKDEPQRE TLKAIHYALN CCGLAGGVEQ FISDICPKKD VLETFTVKSC PDAIKEVFDN KFHI; Positive Samples: Mouse kidney; Cellular Location: Cell membrane, Membrane, Multi-pass membrane protein靶标信息CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. CD9 belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression plays a critical role in the suppression of cancer cell motility and metastasis. CD9 is also considered as metastasis suppressor in solid tumors.
QQ:1749072012