CD5 Monoclonal Antibody (L17F12), FITC, eBioscience™
货号：11-0058-42
规格：100 tests
价格：1888
产品类型：流式抗体
品牌：eBioscience
抗原：CD5
物种：人
宿主：小鼠
抗体亚型：IgG2a, kappa
克隆号：L17F12
荧光染料：FITC
| 抗体类型: | 流式抗体 | 同型对照： | Mouse IgG2a kappa Isotype Control (eBM2a), FITC, eBioscience™ |
| 浓度： | 5 µL/Test | 用法： | 5 µL (0.125 µg)/test (Flow） |
| 产品详细信息Description: The L17F12 monoclonal antibody reacts with human CD5, a 67 kDa protein expressed by a majority of thymocytes and mature T cells and a subset of B cells. Signaling through the CD5 molecule activates T cells and binding of CD5 to its ligand on B cells, CD72, and plays an important role in T-B interaction and proliferation.Applications Reported: This L17F12 antibody has been reported for use in flow cytometric analysis.Applications Tested: This L17F12 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.125 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.Filtration: 0.2 µm post-manufacturing filtered. 靶标信息CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. CD5 is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome. |
| 数据 |
CD5 Antibody (11-0058-41) in Flow Staining of normal human peripheral blood cells with Anti-Human CD19 PE (Product # 12-0199-80) and Mouse IgG2a K Isotype Control FITC (Product # 11-4724-42) (left) or Anti-Human CD5 FITC (right). Cells in the lymphocyte gate were used for analysis. |
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| 参考文献： |
| 1.Genome medicine High-dimensional assessment of B-cell responses to quadrivalent meningococcal conjugate and plain polysaccharide vaccine. |
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