VRK1 Polyclonal Antibody
货号：PA5-81887
规格：100 µL
价格：6049
产品类型：标签抗体
品牌：Thermo Fisher
抗原：Recombinant protein corresponding to Human VRK1
物种：人/小鼠
宿主：驴
抗体亚型：IgG
荧光染料：Alexa Fluor 488
| 类型: | 一抗 | 同型对照： | |
| 浓度： | 0.1 mg/mL | 用法： | 0.25-2 µg/mL(ICC);0.25-2 µg/mL(IF)；1:50-1:200（IHC(P)）0.04-0.4 µg/mL(WB) |
产品详细信息Immunogen sequence: KAAQAGRQSS AKRHLAEQFA VGEIITDMAK KEWKVGLPIG QGGFGCIYLA DMNSSESVGS DAPCVVKVEP SDNGPLFTEL KFYQRAAKPE QIQKWIRTRK LKYLGVPKYW GSGLHDKNGK SYRFMIMDRF GSDLQKI 靶标信息Human vaccinia-related kinase 1 (VRK1) is a new kinase related to a poxvirus kinase, and more distantly to the casein kinase 1 family. VRK1 shows strong autophosphorylating activity in several Ser and Thr residues. VRK has also been found to be an upstream regulator of p53 that belongs to a new signaling pathway.
| 数据： |
| VRK1 Antibody (PA5-81887) in IF Immunofluorescent analysis of VRK1 in U-251 MG cells using a VRK1 polyclonal antibody (Product # PA5-81887). The analysis shows localization to nucleoplasm.Knockdown
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.VRK1 Antibody (PA5-81887)Antibody specificity was demonstrated by siRNA mediated knockdown of target protein. Rh30 were transfected with, control siRNA, VRK1 siRNA (probe #1), and VRK1 siRNA (probe #2) and a decrease in signal intensity was observed in Western Blot application using anti-VRK1 Polyclonal Antibody (Product # PA5-81887) used at a dilution of 0.4 µg/ml. Anti-PPIB was used as a loading control. Knockdown validation info. |
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QQ:1749072012
