KMT2C Polyclonal Antibody
货号：PA5-67359
规格：100 µL
价格：6049
产品类型：标签抗体
品牌：Thermo Fisher
抗原：Recombinant Human KMT2C
物种：人
宿主：兔
抗体亚型：IgG
荧光染料：其它
| 类型: | 一抗 | 同型对照： | |
| 浓度： | 0.2 mg/mL | 用法： | 0.25-2 µg/mL(ICC);0.25-2 µg/mL(IF) |
产品详细信息Immunogen sequence: TPPTMSQPTFP MVPQQLQHQQ HTTVISGHTS PVRMPSLPGW QPNSAPAHLP LNPPRIQPPI AQLPIKTCTP APGTVSNANP QHighest antigen sequence identity to the following orthologs - mouse 88%, rat 33%. 靶标信息Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.
| 数据： |
| KMT2C Antibody (PA5-67359) in IFImmunofluorescent staining of KMT2C in human cell line U-2 OS shows localization to nucleoplasm. Samples were probed using a KMT2C Polyclonal Antibody (Product # PA5-67359). |
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QQ:1749072012