EHMT1 Polyclonal Antibody
货号：PA5-111499
规格：100 µL
价格：6301
产品类型：标签抗体
品牌：Thermo Fisher
抗原：Recombinant Protein corresonding to Human EHMT1
物种：人
宿主：兔
抗体亚型：IgG
荧光染料：其它
| 类型: | 一抗 | 同型对照： | |
| 浓度： | | 用法： | 0.25-2 µg/mL(ICC);0.25-2 µg/mL(IF) |
产品详细信息Immunogen sequence: ADGETNGSCE NSDASSHANA AKHTQDSARV NPQDGTNTLT RIAENGVSER DSEAAKQNHV TADDFVQTSV IGSNGYILNK PALQAQPLRT TSTLASSLPG HAAKTLPGGA GKGRTPSAFP QTPAAPPATL 靶标信息EHMT1, also known as EUHMTASE1, is a histone methyltransferase. This protein methylates 'Lys-9' of histone H3 in vitro. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.
| 数据： |
| EHMT1 Antibody (PA5-111499) in ICCImmunofluorescent staining of EHMT1 in human cell line MCF7 using EHMT1 Polyclonal Antibody (Product # PA5-111499) shows localization to nucleoplasm and nuclear bodies. |
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