Human PDGF-C ELISA Kit/人PDGF-C ELISA试剂盒
货号：EH365RB,EH365RBX5,EH365RBX10
规格：96 tests,5X96 tests,10X96 tests
价格：6641,29884,57271
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：人
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 0.81 ng/mL |
| 检测范围 | 0.81-200 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | PDGF-C |
| Protein aliases | Fallotein, PDGF-C, PDGFC latent form, PDGFC receptor-binding form, Platelet-derived growth factor C, latent form, receptor-binding form, SCDGF, secretory growth factor-like protein, Spinal cord-derived growth factor, VEGF-E |
物种（Tested） | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | FALLOTEIN, PDGFC, SCDGF, UNQ174/PRO200 |
| Gene ID | (Human) 56034 |
| Gene symbol | PDGFC |
| UniProt ID | (Human) Q9NRA1 |
| Human PDGF-C quantitates human PDGF-C in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human PDGF-C.人PDGF-C定量检测血清，血浆，上清液中的人PDGF-C。该检测试剂盒将只识别天然和重组人PDGF-C。Target information 靶标信息Sphingosine Kinase 2 (Sphk2) catalyzes the phosphorylation of sphingosine to sphingosine 1 phosphate (S1P), an important signaling molecule with intra- and extracellular functions. Inside the cell S1P acts as a signaling molecule like other sphingolipid metabolites like ceramide and sphingosine. S1P has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis. The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors).These receptors couple to multiple G proteins (e.g. S1P1 couples to Gi whereas S1P2 and S1P3 couple to Gq, G13 in addition to Gi) and regulate a extremely wide range of cellular events including cell motility, survival, apoptosis, migration and cellcell interaction. Important roles for S1P have also been reported in regulation of cardiogenesis, vascular maturation, oocyte survival, immune cell trafficking, cells of the neuronal system and bone cells. S1P levels are regulated by the activity of Sphk (Sphk1 and Sphk2).鞘氨醇激酶2（Sphk2）催化鞘氨醇磷酸化为鞘氨醇1磷酸酯（S1P），这是一种具有细胞内和细胞外功能的重要信号分子。在细胞内部，S1P像其他鞘脂代谢产物（如神经酰胺和鞘氨醇）一样充当信号分子。 S1P与调节细胞分化，从细胞内存储中的钙动员和细胞凋亡有关。 S1P的细胞表面受体是EDG家族的G蛋白偶联受体（S1P受体）。这些受体与多个G蛋白偶联（例如，S1P1与Gi偶联，而S1P2和S1P3与Gq，G13除Gi偶联）并调节广泛的细胞事件，包括细胞运动，存活，凋亡，迁移和细胞相互作用。还报道了S1P的重要作用，其在心脏发生，血管成熟，卵母细胞存活，免疫细胞运输，神经系统细胞和骨细胞的调节中起作用。 S1P水平受Sphk（Sphk1和Sphk2）的活动调节。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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