IgD Monoclonal Antibody (10.4.22), Functional Grade, eBioscience™/IgD 单抗 (10.4.22), 功能抗体, eBioscience™
货号：16-5924-82,16-5924-85,16-5924-38,16-5924-025,16-5924-050
规格：100 µg,500 µg,5 mg,25 mg,50 mg
价格：934,1752,24089,72266,120443
产品类型：流式抗体
品牌：eBioscience
抗原：IgD
物种：小鼠
宿主：小鼠
抗体亚型：IgG2a, kappa
克隆号：10.4.22
荧光染料：Alexa Fluor 488
_ueditor_page_break_tag_
类型: | 一抗(功能抗体） | 同型对照： | Mouse IgG2a kappa Isotype Control (eBM2a), Functional Grade, eBioscience™ |
浓度： | 1 mg/mL | 用法： | Assay-Dependent（FN） |
产品详细信息Description: This 10.4.22 monoclonal antibody reacts with the a allotype of mouse IgD, which is expressed by mature peripheral B cells. This antibody has been reported to activate B cells via engagement of the IgD receptor. The use of anti-IgM as a polyclonal B cell activator is problematic due to interference from high levels of circulating serum IgM.Crossblocking studies suggest that the 10.4.22 antibody recognizes a different epitope from 11-26c.Applications Reported: This 10.4.22 antibody has been reported for use in functional assays.Applications Tested: This 10.4.22 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.25 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Storage and handling: Use in a sterile environment.Filtration: 0.2 µm post-manufacturing filtered.Purity: Greater than 90%, as determined by SDS-PAGE.Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by LAL assay.Aggregation: Less than 10%, as determined by HPLC.靶标信息This type I transmembrane protein is co-expressed on the surface of mature naive B cells with membrane IgM. IgD also exists as a soluble form in blood serum. Studies have demonstrated that IgD associates with the B cell receptor and participates in mediating signal transduction upon antigen binding.仅用于科研。不用于诊断过程。未经明确授权不得转售。
推荐产品： |
| 二抗荧光二抗免疫组化一抗标签抗体 |
参考文献： |
| 功能检测1.Journal of immunology (Baltimore, Md. : 1950)IL-4 regulates Bim expression and promotes B cell maturation in synergy with BAFF conferring resistance to cell death at negative selection checkpoints."16-5924 was used in Functional assays to analyze the effect of IL-4 on B cell maturation, and its influence on BCR-mediated negative selection."AuthorsGranato A,Hayashi EA,Baptista BJ,Bellio M,Nobrega A |
©
Bio-Rad伯乐代理官网-伯乐抗体-伯乐层析Aminex色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：
https://www.biorod.cn/thread-26308.htm
QQ:1749072012