| 1.OncoimmunologyDistinct clinical patterns and immune infiltrates are observed at time of progression on targeted therapy versus immune checkpoint blockade for melanoma."14-1347 was used in Immunohistochemistry to suggest that antitumor immune responses should be assessed when considering therapeutic options for patients with melanoma."AuthorsCooper ZA,Reuben A,Spencer CN,Prieto PA,Austin-Breneman JL,Jiang H,Haymaker C,Gopalakrishnan V,Tetzlaff MT,Frederick DT,Sullivan RJ,Amaria RN,Patel SP,Hwu P,Woodman SE,Glitza IC,Diab A,Vence LM,Rodriguez-Canales J,Parra ER,Wistuba II,Coussens LM,Sharpe AH,Flaherty KT,Gershenwald JE,Chin L,Davies MA,Clise-Dwyer K,Allison JP,Sharma P,Wargo JA2.NPJ genomic medicineGenomic and immune heterogeneity are associated with differential responses to therapy in melanoma."14-1347 was used in Immunohistochemistry on paraffin embedded tissues to yield insight into differential therapeutic responses to targeted therapy and immune checkpoint blockade in melanoma, and have key translational implications in the age of precision medicine."AuthorsReuben A,Spencer CN,Prieto PA,Gopalakrishnan V,Reddy SM,Miller JP,Mao X,De Macedo MP,Chen J,Song X,Jiang H,Chen PL,Beird HC,Garber HR,Roh W,Wani K,Chen E,Haymaker C,Forget MA,Little LD,Gumbs C,Thornton RL,Hudgens CW,Chen WS,Austin-Breneman J,Sloane RS,Nezi L,Cogdill AP,Bernatchez C,Roszik J,Hwu P,Woodman SE,Chin L,Tawbi H,Davies MA,Gershenwald JE,Amaria RN,Glitza IC,Diab A,Patel SP,Hu J,Lee JE,Grimm EA,Tetzlaff MT,Lazar AJ,Wistuba II,Clise-Dwyer K,Carter BW,Zhang J,Futreal PA,Sharma P,Allison JP,Cooper ZA,Wargo JA3.International journal of cancerICOS+Foxp3+TILs in gastric cancer are prognostic markers and effector regulatory T cells associated with Helicobacter pylori."14134782 was used in flow cytometry to establish the T Cell receptor-inducible costimulator as a promising target for direct T regulatory cell-targeting therapeutic agents for gastric cancer"AuthorsNagase H,Takeoka T,Urakawa S,Morimoto-Okazawa A,Kawashima A,Iwahori K,Takiguchi S,Nishikawa H,Sato E,Sakaguchi S,Mori M,Doki Y,Wada H4.International journal of cancerSelective targeting of Toll-like receptors and OX40 inhibit regulatory T-cell function in follicular lymphoma."14-1347 was used in Flow cytometry/Cell sorting to assess novel adjuvants that may enhance the efficacy of antitumour immunotherapeutic strategies by inhibiting Tregs."AuthorsVoo KS,Foglietta M,Percivalle E,Chu F,Nattamai D,Harline M,Lee ST,Bover L,Lin HY,Baladandayuthapani V,Delgado D,Luong A,Davis RE,Kwak LW,Liu YJ,Neelapu SS |
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