Rabbit anti Human CD324 antibody
货号:VPA00934
规格:100 µl
价格:2746
产品类型:免疫组化一抗
品牌:Bio-Rad
抗原:CD324
物种:人
宿主:兔
抗体亚型:IgG
荧光染料:Purified
产品介绍 | | |
Rabbit anti Human CD324 antibodyrecognizes cadherin-1, also known as CAM 120/80, E-cadherin, epithelial cadherin, calcium-dependent adhesion protein-epithelial and uvomorulin.CDH1 is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in CDH1 are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites (provided by RefSeq, Jul 2008).Rabbit anti Human CD324 antibody detects a band of 135 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
产品详情 | | |
Target Species | Human |
Product Form | Purified IgG - liquid |
Preparation | Rabbit polyclonal antibody purified by affinity chromatography on immunogen |
Buffer Solution | Phosphate buffered saline |
Preservative Stabilisers | 0.09% Sodium Azide<50% Glycerol |
Immunogen | Synthetic peptide of human CD324 |
Acknowledgements | PrecisionAb is a trademark of Bio-Rad Laboratories |
Regulatory | For research purposes only |
Guarantee | 12 months from date of despatch |
存储条件 | | |
Store undiluted at -20°C, avoiding repeated freeze thaw cycles |
应用 | | |
Application Name | Verified | Min Dilution | Max Dilution |
Western Blotting | √ | | |
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
推荐产品 |
Description | Product Code | Applications | Pack Size |
Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml |
技术参数 产品应用 WB
产品类型 PrecisionAb Polyclonal
推荐用于 WB