Rabbit anti Human CD172a antibody
货号：VPA00925
规格：100 µl
价格：2975
产品类型：免疫组化一抗
品牌：Bio-Rad
抗原：CD172a
物种：人
宿主：兔
抗体亚型：IgG
荧光染料：Purified
| 产品介绍 | | |
| Rabbit anti Human CD172a antibodyrecognizes CD172a, also known as CD172 antigen-like family member A, inhibitory receptor SHPS-1, macrophage fusion receptor, myd-1 antigen and tyrosine phosphatase SHP substrate 1.The protein encoded by SIRPA is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. SIRPA and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for SIRPA (provided by RefSeq, Jul 2008).Rabbit anti Human CD172a antibody detects a band of 85 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG - liquid |
| Preparation | Rabbit polyclonal antibody purified by affinity chromatography on immunogen |
| Buffer Solution | Phosphate buffered saline |
| Preservative Stabilisers | 0.09% Sodium Azide |
| Immunogen | Recombinant protein of the C terminal region of human CD172a |
| Acknowledgements | PrecisionAb is a trademark of Bio-Rad Laboratories |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| Store undiluted at -20°C, avoiding repeated freeze thaw cycles |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Western Blotting | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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技术参数 产品应用 WB
产品类型 PrecisionAb Polyclonal
推荐用于 WB
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