Hamster anti Mouse CD103:FITC
货号:MCA4705F
规格:0.1 mg
价格:2576
产品类型:免疫组化一抗
品牌:Bio-Rad
抗原:CD103
物种:小鼠
宿主:其它
抗体亚型:IgG1, kappa
荧光染料:Alexa Fluor 488
产品介绍 | | |
Hamster anti Mouse CD103 antibody, clone 2E7recognizes mouse CD103, otherwise known as integrin alpha-E. CD103 binds Integrin beta 7 to form the heterodimeric integrin molecule αEβ7. This complex is sometimes referred to as CD103, though strictly speaking CD103 only refers to the alpha chain. The beta 7 subunit can also interact with other integrin alpha chains. The αEβ7 complex is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocyes to epithelial cell monolayers. CD103 is expressed on intestinal intraepithelial lymphocytes and is highly expressed on regulatory T cells. Hamster anti Mouse CD103 antibody, clone 2E7 is expected to also recognize the intact αEβ7 complex. |
产品详情 | | |
Target Species | Mouse |
Product Form | Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid |
Preparation | Purified IgG prepared by affinity chromatography |
Buffer Solution | Phosphate buffered saline |
Preservative Stabilisers | <0.1% Sodium Azide (NaN3) |
Immunogen | Mouse intestinal intraepithelial lymphocytes |
Approx. Protein Concentrations | IgG concentration 0.5 mg/ml |
Max Ex/Em | Fluorophore | Excitation Max (nm) | Emission Max (nm) |
FITC | 490 | 525 |
Regulatory | For research purposes only |
Guarantee | 12 months from date of despatch |
存储条件 | | |
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
应用 | | |
Application Name | Verified | Min Dilution | Max Dilution |
Flow Cytometry | √ | 1/5 | |
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
同型对照 |
Description | Product Code | Applications | Pack Size |
Hamster (Armenian) IgG Negative Control:FITC | MCA2356F | F | 100 Tests |
文献 |
1.Lefrançois, L.et al.(1994) Developmental expression of the alpha IEL beta 7 integrin on T cell receptor gamma delta and T cell receptor alpha beta T cells.Eur J Immunol. 24: 635- 640 |
技术参数 产品应用 Flow
产品类型 单克隆抗体
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