| 产品介绍 | | |
| Mouse anti Human HLA DR antibody, clone L243recognizes the human HLA DR antigen, a member of the MHC class II family, which is expressed by B cells, activated T cells and monocytes. Mouse anti Human HLA DR antibody, clone L243 binds to a conformational epitope on HLA DRα and does not cross react with HLA DQ and HLA DP. |
| 产品详情 | | |
| Target Species | Human |
| Species Cross-Reactivity | Target Species | Cross Reactivity |
| Chimpanzee | √ |
| Baboon | √ |
| Product Form | Purified IgG - liquid |
| Preparation | Purified IgG prepared by affinity chromatography |
| Buffer Solution | Phosphate buffered saline |
| Approx. Protein Concentrations | IgG concentration 0.5 mg/ml |
| Preservative Stabilisers | 0.09% Sodium Azide (NaN3) |
| Regulatory | For research purposes only |
| Guarantee | Guaranteed for 12 months from the date of despatch or until the date of expiry, whichever comes first. Please see label for expiry date. |
| 存储条件 | | |
| Store at +4℃. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Flow Cytometry | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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| 文献 |
| 1.Wang, D.et al.(2002) The influence of HLA-DR4 (0401) on the immune response to type II collagen and the development of collagen induced arthritis in mice.J Autoimmun. 18 (2): 95-103.2.Chaturvedi, C.P.et al.(2018) Altered Expression of Hematopoiesis Regulatory Molecules in Lipopolysaccharide-Induced Bone Marrow Mesenchymal Stem Cells of Patients with Aplastic Anemia.Stem Cells Int. 2018: 6901761.3.Kim, S.H.et al.(2019) Forkhead box O1 (FOXO1) controls the migratory response of Toll-like receptor (TLR3)-stimulated human mesenchymal stromal cells.J Biol Chem. 294 (21): 8424-37.4.Temme, S.et al.(2019) Assembly, Intracellular Transport, and Release of MHC Class II Peptide Receptors.Methods Mol Biol. 1988: 297-314. |
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