TCF2 Polyclonal Antibody
货号：PA124459
规格：50 µg
价格：5901
产品类型：抗体和染料
品牌：Thermo Fisher
物种：人
宿主：兔
抗体亚型：IgG
荧光染料：其它
| 类型: | 多抗 | 同型对照： | |
| 浓度： | 0.5 mg/mL | 用法： | 0.2-2.5 µg/mL(WB) |
产品详细信息Recommended positive controls: Jurkat.Predicted reactivity: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%.Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.靶标信息Hepatocyte Nuclear Factor 1 (HNF1, Homeoprotein LFB3, Transcription factor 2, TCF2, Variant hepatic nuclear factor) is a member of the homeodomain-containing superfamily of transcription factors. It is a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. HNF1has been shown to function in nephron development and regulates development of the embryonic pancreas. Mutations in the gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of the gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
| 数据 |
| TCF2 Antibody (PA1-24459) in WBWestern Blot analysis of TCF2 was performed by loading Jurkat cells. Proteins were transferred to a membrane and probed with a TCF2 Polyclonal Antibody (Product # PA1-24459) at a dilution of 0.2-1 µg/mL. |
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