Applications

FA

Synonyms:

RepSox, 2-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine, ALK5 Inhibitor II, E616452

Formulation:

Crystalline solid

Chemical Name:

2-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine

Molecular Formula:

C₁₇H₁₃N₅

Molecular Weight:

287.3

CAS Number

446859-33-2

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

References:

Woltjen, K., & Stanford, W. L. (2009). Inhibition of Tgf-β Signaling Improves Mouse Fibroblast Reprogramming.Cell stem cell,5(5), 457-458.

Larsen, D. M. (2013).Evaluation of the TGF-beta inhibitor RepSox on the expression of pluripotency pathways in murine and bovine cells. UTAH STATE UNIVERSITY.

Jajosky, A. N., Coad, J. E., Vos, J. A., Martin, K. H., Senft, J. R., Wenger, S. L., & Gibson, L. F. (2014). RepSox Slows Decay of CD34+ Acute Myeloid Leukemia Cells and Decreases T Cell Immunoglobulin Mucin-3 Expression.Stem cells translational medicine,3(7), 836.