ID-8

2024-10-15

ID-8

货号:1474669-10,1474669-25

规格:10mg,25mg

价格:1100,2420

产品类型:小分子化合物

品牌:Biogems

Catalogue Number :1474669

Description

ID-8 inhibits tyrosine phosphorylation-regulated kinases and is used to maintain the pluripotency and sustain self-renewal of mouse embryonic stem cells. It is also reported to stimulate proliferation and enhance Wnt-mediated human embryonic cell survival

Additional Information

Applications

FA

Synonyms:

ID 8, 1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol, AC1LGAMV, HY-15838

Formulation:

Crystalline solid

Chemical Name:

1-(4-methoxyphenyl)-2-methyl-3-nitroindol-6-ol

Molecular Formula:

C16H14N2O4

Molecular Weight:

298.3

CAS Number

147591-46-6

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

References:

Kochegarov, A. (2009). Small molecules for stem cells.

Hasegawa, K., Yasuda, S. Y., Teo, J. L., Nguyen, C., McMillan, M., Hsieh, C. L., ... & Kahn, M. (2012). Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion.Stem cells translational medicine,1(1), 18-28.

Miyabayashi, T., Yamamoto, M., Sato, A., Sakano, S., & Takahashi, Y. (2008). Indole derivatives sustain embryonic stem cell self-renewal in long-term culture.Bioscience, biotechnology, and biochemistry,72(5), 1242-1248.

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