IBMX

2024-10-15

IBMX

货号:2885842-250,2885842-50

规格:250mg,50mg

价格:825,220

产品类型:小分子化合物

品牌:Biogems

Catalogue Number :2885842

Description

IBMX is a general inhibitor of cyclic nucleotide phosphodiesterases, increasing the level of intracellular cAMP. It is used to increase cell differentiation, decrease proliferation, and induce apoptosis. IBMX is reported to inhibit TNF-alpha, reduce inflammation, and activate PKA.

Additional Information

Applications

FA

Synonyms:

1-Methyl-3-isobutylxanthine, 3-Isobutyl-1-methylxanthine, Isobutyltheophylline

Formulation:

Crystalline solid

Chemical Name:

1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione

Molecular Formula:

C10H14N4O2

Molecular Weight:

222.3

CAS Number

28822-58-4

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

References:

Usachev, Y., & Verkhratsky, A. (1995). IBMX induces calcium release from intracellular stores in rat sensory neurones.Cell calcium,17(3), 197-206.

Tio, M., Tan, K. H., Lee, W., Wang, T. T., & Udolph, G. (2010). Roles of db-cAMP, IBMX and RA in aspects of neural differentiation of cord blood derived mesenchymal-like stem cells.PLoS One,5(2), e9398.

Hube, F., Lee, Y. M., Röhrig, K., & Hauner, H. (1999). The phosphodiesterase inhibitor IBMX suppresses TNF-alpha expression in human adipocyte precursor cells: a possible explanation for its adipogenic effect.Hormone and metabolic research= Hormon-und Stoffwechselforschung= Hormones et metabolisme,31(6), 359-362.

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