25mg

2024-10-15

25mg

货号:3009078-25,3009078-10

规格:25mg,10mg

价格:3575,1595

产品类型:小分子化合物

品牌:Biogems

Catalogue Number :3009078

Description

OAC-1 activates OCT-4, a transcription factor involved in the self-renewal of undifferentiated stem cells. It is commonly used to enhance the efficiency of reprogramming embryonic fibroblasts. OAC-1 does not seem to effect Wnt-Beta-catenin signaling or the pt3-p21 pathway.

Additional Information

Applications

FA

Synonyms:

BAS 00287861, OAC1, AC1LG6VC

Formulation:

Crystalline solid

Chemical Name:

N-(1H-pyrrolo[2,3-c]pyridin-5-yl)benzamide

Molecular Formula:

C14H11N3O

Molecular Weight:

237.3

CAS Number

300586-90-7

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

References:

Li, W., Tian, E., Chen, Z. X., Sun, G., Ye, P., Yang, S., ... & Shi, Y. (2012). Identification of Oct4-activating compounds that enhance reprogramming efficiency.Proceedings of the National Academy of Sciences,109(51), 20853-20858.

Huang, X., Cooper, S., & Broxmeyer, H. E. (2014). Activation of OCT4 Enhances Ex Vivo Expansion of Phenotypically Defined and Functionally Engraftable Human Cord Blood Hematopoietic Stem and Progenitor Cells By Regulating HOXB4 Expression.Blood,124(21), 4332-4332.

Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., & Yamanaka, S. (2007). Induction of pluripotent stem cells from adult human fibroblasts by defined factors.cell,131(5), 861-872.

技术参数
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