Applications

FA

Synonyms:

1,9-Pyrazoloanthrone, SP600125, Pyrazolanthrone, Anthrapyrazolone

Formulation:

Crystalline solid

Chemical Name:

anthra[1,9-cd]pyrazol-6(2H)-one

Molecular Formula:

C₁₄H₈N₂O

Molecular Weight:

220.2

CAS Number

129-56-6

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

References:

Xia, H. H. X., He, H., De Wang, J., Gu, Q., Lin, M. C., Zou, B., ... & Wong, B. C. Y. (2006). Induction of apoptosis and cell cycle arrest by a specific c-Jun NH 2-terminal kinase (JNK) inhibitor, SP-600125, in gastrointestinal cancers.Cancer letters,241(2), 268-274.

Roy, P. K., Rashid, F., Bragg, J., & Ibdah, J. A. (2008). Role of the JNK signal transduction pathway in inflammatory bowel disease.World journal of gastroenterology: WJG,14(2), 200.

Bennett, B. L., Sasaki, D. T., Murray, B. W., O'Leary, E. C., Sakata, S. T., Xu, W., ... & Anderson, D. W. (2001). SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase.Proceedings of the National Academy of Sciences,98(24), 13681-13686.