Recombinant Human BMP-3

2024-10-15

Recombinant Human BMP-3

货号:120-24B-10,120-24B-100,120-24B-1000,120-24B-250,120-24B-50,120-24B-500

规格:10ug,100ug,1mg,250ug,50ug,500ug

价格:643,3522,14134,6168,1568,9165

产品类型:细胞因子添加物

品牌:PeproTech

产品描述:TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth, and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. BMP-3 is abundantly found in adult bone and, to a lesser extent, fetal cartilage. BMP-3 inhibits osteogenesis and bone formation by activating a signaling cascade that antagonizes the signaling of pro-osteogenic BMPs. Recombinant Human BMP-3 is a disulfide-linked homodimeric protein that corresponds to residues 361 to 472 of the 472 amino acid BMP-3 precursor protein. The calculated molecular weight of Recombinant Human BMP-3 is 25.2 kDa.来源:E.coli别名:Bone Morphogenetic Protein-3, Osteogenin, BMP-3A氨基酸序列:MQWIEPRNCA RRYLKVDFAD IGWSEWIISP KSFDAYYCSG ACQFPMPKSL KPSNHATIQS IVRAVGVVPG IPEPCCVPEK MSSLSILFFD ENKNVVLKVY PNMTVESCAC R纯度:≥ 95% by SDS-PAGE gel and HPLC analyses.生物活性:Determined by its ability to inhibit BMP-2-induced alkaline phosphatase production by ATDC-5 cells.Calculated Molecular Weight:25.2 kDaAccession Number:P12645Gene ID:651交叉反应:Mouse

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