货号：AF-310-13-5

规格：5µg

价格：982.5

产品类型：细胞因子添加物

品牌：PeproTech

AF-310-13

别名:

B cell Activating Factor belonging to the TNF family, TNFSF13B, TNFSF20, TALL-1, BLyS, THANK, ZTNF4

描述:

BAFF, a member of the TNF family of ligands, is expressed in T cells, macrophages, monocytes and dendritic cells. BAFF is involved in stimulation of B and T cell function, and is an important survival and maturation factor for peripheral B cells. BAFF signals through three different TNF receptors, TACI, BCMA and BAFF-R. The human BAFF gene codes for a 285 amino acid type II transmembrane protein containing a 46 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 218 amino acid extracellular domain. Recombinant Human soluble BAFF is a 152 amino acid polypeptide (17.0 kDa), which contains the TNF-like portion of the extracellular domain of BAFF.Manufactured using all Animal-Free reagents.

氨基酸序列:

AVQGPEETVT QDCLQLIADS ETPTIQKGSY TFVPWLLSFK RGSALEEKEN KILVKETGYF FIYGQVLYTD KTYAMGHLIQ RKKVHVFGDE LSLVTLFRCI QNMPETLPNN SCYSAGIAKL EEGDELQLAI PRENAQISLD GDVTFFGALK LL

来源:

E.coli

纯度:

Greater than 95% by SDS-PAGE gel and HPLC analyses.

生物活性:

Determined by a mouse splenocyte survival assay. The expectedED₅₀for this effect is 0.5-2.0 µg/ml.

交叉反应:

Human, Mouse

除了5ug，还提供：20μg；100μg； 250μg；500μg；1mg，详情咨询：010-57438396