Primocin™抗生素

2024-10-16

Primocin™抗生素

货号:ant-pm-1

规格:500 mg (10 x 1 ml)

价格:2645

产品类型:抗生素和支原体预防

品牌:InvivoGen

Antimicrobial Agent for Primary Cells

Primocin™ is an antibiotic formulation specifically designed to protect primary cell lines from cell culture contaminations. Primocin™ is active against both Gram+ and Gram- bacteria, mycoplasmas and fungi.Primocin™ is the first formulation to offer complete protection against microbial contaminants. There is no need to add Pen-Strep.Primocin™ is non-toxic to primary cells. It acts on targets found only in micro-organisms. Bacterial targets are the DNA gyrase and the prokaryotic ribosomal subunits, 30S and 50S. The fungal target is ergosterol, a molecule only found in the cell membrane of fungi and yeasts.

Primocin has been used successfully in many primary cells, including mouse- and human-tumor derived cell lines [1], embryonic cells [2] and induced pluripotent stem cells [3-6].

    Specifications

    Product concentration: 50 mg/ml

    Recommended working concentration: 100 μg/ml

    One ml Primocin™ is enough to treat 500 ml medium

    Shipped at room temperature

    Contents

    Primocin™ is providedas a cell culture tested, sterile filtered light yellow solution at a concentration of 50 mg/ml in different formats:

    - 10 x 1 ml vial (500 mg)

    - 1 x 20 ml bottle (1 g)

    Recent articles using InvivoGen Primocin™

    • 2017- Biomaterials., 128:44-55.A microengineered collagen scaffold for generating a polarized crypt-villus architecture of human small intestinal epithelium.Wang Y. et al.

    • 2017- J Biol Chem., [Epub ahead of print]ETS Proto-Oncogene 1 Transcriptionally Up-regulates the Cholangiocyte Senescence-associated Protein Cyclin Dependent Kinase Inhibitor 2A.O'Hara SP. et al.

    • 2017- J Neurosci., 37(21):5309-5318.Decreased Motor Neuron Support by SMA Astrocytes due to Diminished MCP1 Secretion.Martin JE. et al.

    • 2017- Gene Ther., Epub ahead of print]Use of a gamma-2 herpesvirus as a vector to deliver antibodies to rhesus monkeys.Bischof GF. et al.

    • 2017- Oncotarget., 8(9):14860-14875.Disabled cell density sensing leads to dysregulated cholesterol synthesis in glioblastoma.Kambach DM. et al.

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