Primocin™抗生素
货号:ant-pm-1
规格:500 mg (10 x 1 ml)
价格:2645
产品类型:抗生素和支原体预防
品牌:InvivoGen
Antimicrobial Agent for Primary Cells
Primocin™ is an antibiotic formulation specifically designed to protect primary cell lines from cell culture contaminations. Primocin™ is active against both Gram+ and Gram- bacteria, mycoplasmas and fungi.Primocin™ is the first formulation to offer complete protection against microbial contaminants. There is no need to add Pen-Strep.Primocin™ is non-toxic to primary cells. It acts on targets found only in micro-organisms. Bacterial targets are the DNA gyrase and the prokaryotic ribosomal subunits, 30S and 50S. The fungal target is ergosterol, a molecule only found in the cell membrane of fungi and yeasts.
Primocin has been used successfully in many primary cells, including mouse- and human-tumor derived cell lines [1], embryonic cells [2] and induced pluripotent stem cells [3-6].
Specifications
Product concentration: 50 mg/ml
Recommended working concentration: 100 μg/ml
One ml Primocin™ is enough to treat 500 ml medium
Shipped at room temperature
Contents
Primocin™ is providedas a cell culture tested, sterile filtered light yellow solution at a concentration of 50 mg/ml in different formats:
- 10 x 1 ml vial (500 mg)
- 1 x 20 ml bottle (1 g)
Recent articles using InvivoGen Primocin™
2017- Biomaterials., 128:44-55.A microengineered collagen scaffold for generating a polarized crypt-villus architecture of human small intestinal epithelium.Wang Y. et al.
2017- J Biol Chem., [Epub ahead of print]ETS Proto-Oncogene 1 Transcriptionally Up-regulates the Cholangiocyte Senescence-associated Protein Cyclin Dependent Kinase Inhibitor 2A.O'Hara SP. et al.
2017- J Neurosci., 37(21):5309-5318.Decreased Motor Neuron Support by SMA Astrocytes due to Diminished MCP1 Secretion.Martin JE. et al.
2017- Gene Ther., Epub ahead of print]Use of a gamma-2 herpesvirus as a vector to deliver antibodies to rhesus monkeys.Bischof GF. et al.
2017- Oncotarget., 8(9):14860-14875.Disabled cell density sensing leads to dysregulated cholesterol synthesis in glioblastoma.Kambach DM. et al.
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