CD69 Monoclonal Antibody (FN50), FITC

货号：11-0699-41,11-0699-42

规格：25 Tests,100 Tests

价格：835,1880

产品类型：流式抗体

品牌：eBioscience

物种：人

宿主：小鼠

抗体亚型：IgG

克隆号：FN50

荧光染料：FITC

类型:	单抗	同型对照：	Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), FITC
浓度：	5 µL/Test	用法：	5 μL (0.125 μg)/test(Flow)

产品详细信息Description: The FN50 monoclonal antibody reacts with human CD69, also known as very early activation antigen (VEA). CD69 is approximately 30 kDa and is expressed on the cell-surface as a disulfide-linked dimer. CD69 is rapidly upregulated upon activation and expressed on lymphocytes, monocytes and platelets.Applications Reported: The FN50 antibody has been reported for use in flow cytometric analysis.Applications Tested: This FN50 antibody has been pre-titrated and tested by flow cytometric analysis of PHA-stimulated normal human peripheral blood cells. This can be used at 5 µL (0.125 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.Filtration: 0.2 µm post-manufacturing filtered.靶标信息CD69 (AIM, Active Inducer Molecule) is a gp28/34 disulfide bonded homodimer with a molecular weight of 60 kDa under non-reducing conditions. CD69 contains one or two N linked oligosacaride and the molecule is present on activated platelets. In normal peripheral blood a variable percentage of cells express the CD69 antigen, and it is involved in lymphocyte signal transduction. Expression CD69 is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. Alternative splicing results in multiple transcript variants of CD69. Diseases associated with CD69 dysfunction include coccidiodomycosis and asthma.

数据

CD69 Antibody (11-0699-41) in FlowStaining of PHA-stimulated normal human peripheral blood cells with Mouse IgG1 K Isotype Control FITC (Product # 11-4714-42) (open histogram) or Anti-Human CD69 FITC (filled histogram). Cells in the lymphocyte gate were used for analysis.

推荐产品：

二抗荧光二抗免疫组化一抗标签抗体

参考文献：

1.Chinese medicineGlossogyne tenuifolia(Hsiang-ju) extract suppresses T cell activation by inhibiting activation of c-Jun N-terminal kinase."Published figure using CD69 monoclonal antibody (Product # 11-0699-42) in Flow Cytometry"2.The Journal of experimental medicineNovel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy."11-0699 was used in Flow cytometry/Cell sorting to assess whether targeting the neoantigen resulting from the histone 3 variant H3.3K27M mutation is therapeutically viable in T cell-based therapy for glioma."AuthorsChheda ZS,Kohanbash G,Okada K,Jahan N,Sidney J,Pecoraro M,Yang X,Carrera DA,Downey KM,Shrivastav S,Liu S,Lin Y,Lagisetti C,Chuntova P,Watchmaker PB,Mueller S,Pollack IF,Rajalingam R,Carcaboso AM,Mann M,Sette A,Garcia KC,Hou Y,Okada H3.Scientific reportsCombinations of isoform-targeted histone deacetylase inhibitors and bryostatin analogues display remarkable potency to activate latent HIV without global T-cell activation."Published figure using CD69 monoclonal antibody (Product # 11-0699-42) in Flow Cytometry"4.Nature communicationsMAIT cells are activated during human viral infections."11-0699 was used in Flow cytometry/Cell sorting to demonstrate how MAIT cells are activated following viral infections, suggesting a potential role in both host defence and immunopathology."5.Science signalingChemical proteomic map of dimethyl fumarate-sensitive cysteines in primary human T cells."11-0699 was used in Flow cytometry/Cell sorting to explore the mode of action of Dimethyl fumarate as a therapy for autoimmune diseases."AuthorsBlewett MM,Xie J,Zaro BW,Backus KM,Altman A,Teijaro JR,Cravatt BF

技术参数

© Bio-Rad伯乐代理官网-伯乐抗体-伯乐层析Aminex色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：https://www.biorod.cn/thread-22369.htm