Rabbit NCAM-1/CD56 ELISA Kit/兔NCAM-1 / CD56 ELISA试剂盒
货号：ER14RB,ER14RBX5
规格：96 Tests,5X96 Tests
价格：6641,29884
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：兔
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 0.45 ng/mL |
| 检测范围 | 0.45-100 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | CD56 (NCAM) |
| Protein aliases | neural cell adhesion molecule 1 |
物种（Tested） | 兔 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene ID | (Rabbit) 100348118 |
| Gene symbol | NCAM1 |
| Rabbit NCAM-1/CD56 quantitates rabbit NCAM-1/CD56 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rabbit NCAM-1/CD56.兔NCAM-1 / CD56定量测定血清，血浆，上清液中的兔NCAM-1 / CD5。该检测试剂盒将只识别天然和重组兔NCAM-1 / CD56。Target information 靶标信息CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120-180 kDa. CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. Polysialic modification results in reduction of CD56-mediated cell adhesion. Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins. CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma. Further, CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors. Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms.CD56（NCAM，神经细胞粘附分子）是免疫球蛋白家族的跨膜糖蛋白，可作为粘附分子，在神经系统中以120-180 kDa的同工型广泛表达。 CD56存在于T细胞和NK细胞上，并参与细胞迁移，轴突生长，寻路和突触可塑性。多唾液酸修饰导致CD56介导的细胞粘附减少。 CD56通过其细胞外区域，通过结合细胞外基质成分（如层粘连蛋白和整联蛋白）介导同种和异种相互作用。 CD56在大多数神经外胚层衍生的细胞系，组织和肿瘤，例如视网膜母细胞瘤，髓母细胞瘤，星形细胞瘤和神经母细胞瘤中表达。此外，CD56是广泛使用的神经内分泌标记物，其对神经内分泌肿瘤和卵巢颗粒细胞肿瘤具有高敏感性。与CD56功能障碍相关的疾病包括狂犬病和弹状浆细胞样树突状细胞瘤。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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