TER-119 Monoclonal Antibody (TER-119), Functional Grade/TER-119,功能抗体, eBioscience™

2024-10-18

TER-119 Monoclonal Antibody (TER-119), Functional Grade/TER-119,功能抗体, eBioscience™

货号:16-5921-85,16-5921-38,16-5921-025,16-5921-050

规格:500 µg,5 mg,25 mg,50 mg

价格:3423,24089,72266,120443

产品类型:流式抗体

品牌:eBioscience

抗原:TER-119

物种:小鼠

宿主:大鼠

抗体亚型:IgG2b, kappa

克隆号:TER-119

荧光染料:其它

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类型:

一抗(功能抗体)

同型对照:

Rat IgG2b kappa Isotype Control (eB149/10H5), Functional Grade, eBioscience™

浓度:

1 mg/mL

用法:

0.5 µg/test(Flow);Assay-Dependent(对照);Assay-Dependent(功能检测)

产品详细信息Description: The TER-119 monoclonal antibody reacts with mouse erythroid cells from early proerythroblast to mature erythrocyte stages. The TER-119 antigen is present in yolk sac, fetal and newborn liver, but is not expressed by cells carrying BFU-E and CFU-E activities. Several erythroleukemia cell lines tested so far are negative for expression of TER-119 antigen even after dimethylsulfoxide stimulation. Biochemical and molecular analysis of the TER-119 antigen indicate that this molecule is associated with the surface glycophorin A, but is not a typical glycophorin.Applications Reported: The TER-119 antibody has been reported for use in flow cytometric analysis.Applications Tested: The TER-119 antibody has been tested by flow cytometric analysis of mouse splenocytes and bone marrow cells. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Storage and handling: Use in a sterile environment.Filtration: 0.2 µm post-manufacturing filtered.Purity: Greater than 90%, as determined by SDS-PAGE.Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by LAL assay.Aggregation: Less than 10%, as determined by HPLC.靶标信息TER-119 is a lineage marker for erythroid cells from early proerythroblast to mature erythrocyte stages in adult blood, spleen, and bone marrow. It is also present in yolk sac, and fetal and newborn liver. The TER-119 antigen is not expressed by cells of earlier erythroid development at BFU-e (blast-forming unit erythroid) stage or CFU-e (colony-forming unit erythroid) stage.仅用于科研。不用于诊断过程。

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参考文献:

流式1.PLoS geneticsMacrophages fine tune satellite cell fate in dystrophic skeletal muscle of mdx mice."Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry"2.Nature communicationsStem cell factor is selectively secreted by arterial endothelial cells in bone marrow."Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry"3.Breast cancer research : BCRObesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity."Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry"IF4.Development (Cambridge, England)Transient loss of venous integrity during developmental vascular remodeling leads to red blood cell extravasation and clearance by lymphatic vessels."Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Immunofluorescence"5.Biochemical and biophysical research communicationsPostnatal lethality and abnormal development of foregut and spleen in Ndrg4 mutant mice."Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Immunofluorescence"

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