Recombinant Human TACI
货号：310-17-100,310-17-1000,310-17-20,310-17-250,310-17-5,310-17-500
规格：100ug,1mg,20ug,250ug,5ug,500ug
价格：9077,44543,1425,19450,585,28897
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：TACI, a member of the TNF Receptor superfamily, is expressed in the small intestine, spleen, thymus, peripheral blood leukocytes, activated T cells, and resting B cells. TACI can bind to both APRIL and BAFF, stimulate the activation of transcription factors NF-κB and AP-1, and can mediate the calcineurin-dependent activation of NF-AT (nuclear-factor of activated T cells). TACI also plays a key role in the stimulation of B and T cell function. Soluble TACI inhibits APRIL-stimulated proliferation of primary B cells by blocking the binding of APRIL to the membrane-anchored TACI receptor. Recombinant Human TACI is a soluble 159 amino acid polypeptide (17.8 kDa) comprising the TNFR homologous, cysteine-rich extracellular domain of the TACI protein.来源:E.coli别名:Transmembrane activator and CAML interactor, TNFRSF13B氨基酸序列:SGLGRSRRGG RSRVDQEERF PQGLWTGVAM RSCPEEQYWD PLLGTCMSCK TICNHQSQRT CAAFCRSLSC RKEQGKFYDH LLRDCISCAS ICGQHPKQCA YFCENKLRSP VNLPPELRRQ RSGEVENNSD NSGRYQGLEH RGSEASPALP GLKLSADQV纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:Determined by its ability to block human BAFF induced T2B cell survival using a concentration range of 1.0-3.0 µg/ml.Calculated Molecular Weight:17.8 kDaAccession Number:O14836Gene ID:23495Country Of Origin:USA |
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